The 23rd conference on Computational Methods in Systems Biology (CMSB 2025) will take place on September 10th-12th 2025 in Lyon, France, at the Department of Computer Science, University of Lyon.

The aim of the annual CMSB conference series is to bring together researchers from across biological, computational, mathematical and physical sciences interested in the system-level study, modeling, simulation, advanced analysis and  design of biological systems. Information about previous CMSB conferences is available on the permanent CMSB website.

The CMSB 2025 proceedings will be published in the series Lecture Notes in Bioinformatics (LNCS/LNBI) by Springer Nature. The proceedings of the previous editions of CMSB are available on their website. The CMSB 2025 proceedings will be indexed by ISI Web of Science, Scopus, DBLP, and Google Scholar.

CMSB 2024 solicits original research articles, tool papers, posters, and highlight talks on the modelling, analysis or design of biological systems, as well as the analysis of biological data. The conference covers the broad field of computational methods and tools in systems and synthetic biology and their applications in biomedicine and the environment.

The conference welcomes new theoretical results with potential applications to systems and synthetic biology, as well as novel applications and case studies of existing methods, tools, or frameworks.

Topics of interest include, but are not limited to:

• formalisms for modelling biological processes;
• methods and tools for biological system analysis, modelling and simulation;
• frameworks for model verification, validation, analysis, and simulation of biological systems;
• high-performance methods for computational systems biology;
• automated parameter and model inference;
• machine learning and data analytics in biology and biomedicine;
• multi-scale modelling, multi-agent simulation and analysis methods;
• design, analysis, and verification methods for synthetic biology;
• methods for biomolecular computing and engineered molecular devices;
• model integration and biological databases;
• data-based approaches for systems and synthetic biology;
• optimality and control of biological systems;
• modelling, analysis and control of microbial communities and ecosystems.

Contributions should be submitted to one of the following categories:

A) REGULAR PAPERS: Regular papers should describe original work that has not been previously published and is not under review for publication elsewhere. Accepted regular papers will be published as part of the conference proceedings in the Springer LNCS series. Papers in this category should not exceed 15 pages in the Springer LNCS style (including main figures and tables, excluding references and possible appendices).

B) TOOL PAPERS: Tool papers should present new tools or public websites, new tool components or novel extensions to existing tools or websites supporting biological system modelling, analysis, simulation, or similar. Submissions must include information on methods, tool availability, and selected application results. They should be original and not previously published in a similar form. Accepted tool papers will be published as part of the conference proceedings in the Springer LNCS series. Papers in this category should have 4-6 pages in the Springer LNCS style (including main figures and tables, excluding references and possible appendices).

Plus in a later call

C) POSTERS: Extended abstracts should be submitted to propose poster presentation of original unpublished work, or of major results published or accepted in the last year in a high-quality journal or conference. The abstracts should be submitted in Springer LNCS style and should not exceed 4 pages all included. Authors of accepted abstracts will be invited for presentation in a poster session and/or for flash presentations. Poster submissions will not be included in the Springer LNBI proceedings.

D) HIGHLIGHT TALKS: Highlight talk proposals should be submitted in the form of an extended abstract, for possible oral presentation without publication of related material in the conference proceedings. We particularly welcome submissions of recently published work. Submitted abstracts summarising the results and their relevance should not exceed 2 pages including references. Extended abstracts will not be included in the Springer LNBI proceedings.

Two prizes will be delivered for the best regular or tool papers:

• the best paper award
• the best student paper award.

soon coming: program committee list.

10 Feb.:paper submission dates.

5 Feb. 2025: CMSB 2025 webpage is online.